Discount Premarin - Canada Drug Pharmacy

The products listed below either match, relate to, or are possibly therapeutically equivalent to "Premarin". Please note that all prescription products require a VALID PRESCRIPTION written by your doctor to be sent to us to complete your order.


Branded Products

RX REQUIREDPremarin (Conj. Estrogen)0.3mg84Brand$50.00
RX REQUIREDPremarin (Conj. Estrogen)0.45 mg100Brand$277.00
RX REQUIREDPremarin (Conj. Estrogen)0.625mg84Brand$41.00
RX REQUIREDPremarin (Conj. Estrogen)0.9 mg100Brand$268.00
RX REQUIREDPremarin (Conj. Estrogen)1.25mg84Brand$62.00
RX REQUIREDPremarin Cream0.625mg/g14g X 1Brand$29.00
RX REQUIREDPremarin Cream0.625mg/g14g X 2Brand$53.00
RX REQUIREDPremarin Cream0.625mg/g14g X 3Brand$71.00
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Generic Drug for Premarin: Conj. Estrogen

Mechanism of Action

Estrogens produced by ovaries are responsible for the development and maintenance of various hormonal functions and need to be replenished by external sources when normal levels are suppressed. Premarin's conjugated estrogens act by binding to nuclear receptors in estrogen-responsive tissues. These estrogens modulate the pituitary secretion of various hormones like gonadotropins, luteinizing hormone (LH), and follicle stimulating hormone (FSH) via a negative feedback mechanism. Estrogens reduce the increased levels of gonadotropins in postmenopausal women, which in turn suppress FSH and LH in the pituitary gland. This entire process balances the normal estrogen functions in postmenopausal women.

Side-effects and safety profile: Various mild to moderately serious and commonly reported side-effects of Premarin include: headache, nausea, vomiting, abdominal cramps, bloating, fluid retention, breast pain, hair loss, weakness, fatigue, vaginal yeast infection, etc.

Side-effects and safety profile:

Lexapro side-effects seen during various clinical trials are as follows: Serious but less common side-effects include: severe allergic reactions, heart attack, stroke, high BP, hyperglycemia, blood clotting, dementia, breast cancer, uterus lining cancer, ovarian cancer, gallbladder disorders, hepatic problems, enlargement of benign tumors of the uterus, new breast lumps, abnormal vaginal bleeding, altered vision, altered speech, sudden severe headaches, severe chest pains, severe leg pain, shortness of breath, swelling of lips, tongue and face, etc. A rare but serious side-effect called serotonin syndrome may occur when Lexapro is prescribed with other drugs.

Patients experiencing any of the above serious side-effects should seek immediate medical care.


Premarin increases the risk of uterine cancer, whose primary symptom is unusual vaginal bleeding. Reports indicate that estrogens, with or without progestin, may increase the risk of endometrial cancer, heart attacks, strokes, dementia, breast cancer, and blood clots. Therefore, Premarin, with or without progestins, must be prescribed with the lowest effective dose for the shortest possible duration. Premarin therapy is reported to cause deep vein thrombosis (DVT) and dementia in postmenopausal women over 65-year-old.

Premarin is contraindicated in patients with a history of heart attack, stroke, abnormal vaginal bleeding, blood clotting issues, hepatic disease, and breast, uterine, or hormonal cancer. Patients must discuss their medical history with the prescribing physician, especially as regards cardiac issues, seizures, migraines, diabetes, endometriosis, renal disorder, asthma, underactive thyroid, high cholesterol or triglycerides, systemic lupus erythematosus, gallbladder disease and hysterectomy. Premarin is an FDA pregnancy category X drug which means it may cause birth defects to fetus, and thus must not be prescribed in pregnant women. Premarin is an FDA pregnancy category X drug which means it may cause birth defects to fetus, and thus must not be prescribed in pregnant women. Premarin must not be prescribed to nursing women.

Ordering Premarin Online

Do you have questions about purchasing Premarin? Call 1-877-275-1525 or contact us through another method. Once you have placed your order for Premarin, you will be provided with instruction on how to submit your doctors prescription.

Premarin Price Guarantee

Our mission at Canada Drug Pharmacy is to offer Premarin at the most affordable price along with exceptional customer service. We are so confident we have the cheapest price for Premarin, if you find a cheaper price online, use the price beat feature next to the medication and we will beat it.

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